Oxymetholone Side Effects

As long as you plan to run Anadrol – you should learn about Oxymetholone side effects. Anadrol is the most popular brand name for the chemical Oxymetholone. But any brand (trade) name with this substance is basically the same Anadrol. You really should learn about its side effects because this is a harsh steroid. So, before you actually get to use it, you should understand what are the negatives that you may experience during its cycle.

Anadrol (Oxymetholone) has a reputation in bodybuilding as one of the harshest anabolic steroids. It can be extremely helpful, especially when talking about off-season bulking. It may help you gain ridiculous amounts of muscle mass, weight, and strength really fast. But not without any risk as it can be extremely dangerous too. For this reason, you really should learn how to correctly run Oxymetholone to avoid the negatives.

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One of the very first things that come into mind when thinking about Oxymetholone side effects is hepatotoxicity. Because Anadrol is an oral steroid – it is liver toxic, and it’s generally more hepatotoxic than other oral steroids. Due to high hepatotoxicity, it leaves very little length for you to use Anadrol. I do not recommend anyone to use it for longer periods than 4 – 6 weeks. According to studies, using Anadrol for 12 weeks straight is capable of causing nasty issues and I would avoid it.

Moreover, Oxymetholone is a DHT derivative that doesn’t aromatize into estrogen. But despite the fact that it will not increase estrogen, estrogenic side effects are still possible due to its ability to bind to estrogen receptors.

Additionally, as with any other anabolic steroid, androgenic side effects are possible. Plus there’s no way to avoid testosterone suppression or the negative effects on cardiovascular health.

Hepatotoxic Side Effects

When talking about Anadrol side effects, hepatotoxicity is perhaps the most popular. That’s because this is a highly liver-toxic compound that you should be very careful with. This is an oral anabolic steroid. It is coming with the C17 alpha alkylation that allows Oxymetholone to remain highly bioactive when you use it as a tablet (orally). Nonetheless, this is the main contributor to the hepatotoxic effects of this steroid.

According to studies, there is evidence proving that Anadrol is having a considerable amount of hepatotoxicity on the body. Especially when you use it in doses required for bodybuilding purposes. Which are usually starting at 50 mg/day and higher.

The study subjects were HIV-positive patients who were using the compound for a period of 12 weeks. The results indicate that subjects were displaying a significant increase in AST and ALT liver enzymes. In fact, the increase in liver enzymes in some subjects was dangerously high, so high that it could lead to life-threatening liver tumors like hepatitis and other liver issues.

• I strongly recommend avoiding abuse of Anadrol in terms of dosage and cycle length (no more than 4-6 weeks) as well as having an adequate break in between cycles. Additionally, avoid the concomitant use of Anadrol and other liver-toxic substances such as alcohol, some medications, and other C17AA steroids. Moreover, you could help maintain your liver health by running liver support supplements at least during the period of using hepatotoxic steroids. Some examples of such supplements include Milk Thistle, NAC, LIV 52, and others.

HPTA and Natural Testosterone Production Suppression

There are no anabolic and androgenic steroids that wouldn’t cause suppression of natural testosterone. Anadrol (Oxymetholone) is a very powerful steroid and that’s why the suppression is likely to be even worse. Due to its immense power, it is likely to lead to a complete shutdown of HPTA and endogenous testosterone production. For this exact reason, I strongly recommend avoiding the use of Anadrol without the use of some exogenous testosterone form.

• Additionally, after each cycle of anabolic steroids, it’s very important to run a Post Cycle Therapy (PCT). The PCT plan is going to ensure that you will not lose all the gains you’ve made during the cycle and in addition to that – it will help you remain healthy. The PCT plan helps restore natural testosterone production. Without a PCT, you are likely to suffer from low testosterone symptoms.

The symptoms are likely to be really bad considering you would stop a cycle of steroids with a complete shutdown of HPTA and natural testosterone production. So, unless you’re in Testosterone Replacement Therapy (PCT) or cruising (in both cases you receive your testosterone exogenously).

Cardiovascular Side Effects

Again, any anabolic and androgenic steroids are likely to cause cardiovascular issues. That’s because they will all increase your hormone levels which are likely to negatively shift your cholesterol values. The problem with Anadrol is that these side effects are likely to be worse with Anadrol than with other anabolic steroids. In fact, cardiovascular strain is one of the most pronounced and serious Anadrol side effects.

Cardiovascular issues are especially possible with oral steroids because they negatively affect your liver. Now, Oxymetholone is very powerful itself and it has powerful negative effects on your liver. This can lead to serious cholesterol issues. It involves a reduction of HDL cholesterol values (the good ones) and an increase in LDL cholesterol values (the bad ones).

Needless to mention that negative cholesterol changes could lead to various cardiovascular issues such as arteriosclerosis. This coupled with the fact that Anadrol is very likely to increase water retention (will explain below) makes the cardiovascular side effects very possible and very pronounced. It’s highly important for you to maintain your liver healthy and your cholesterol healthy. Additionally, ensure you’re performing proper cardio exercises for your cardiovascular health.

• In the end, make sure that you keep an eye on your blood pressure because, on Anadrol, it is very likely to notice a huge spike in blood pressure. Hypertension, as we all know, is the “silent killer”. Please keep an eye on your cholesterol and blood pressure when attempting to use such powerful compounds as Anadrol.

Androgenic Side Effects

Oxymetholone side effects also include the androgenic ones, pretty much as with any other anabolic and androgenic steroids. All steroids can “speed up” or “cause” some androgenic activity and Anadrol, again, is no exception.

According to studies, this steroid has a lower androgenic activity than Testosterone. While testosterone androgenic activity is 100, the androgenic rating of Oxymetholone is only 45. This means that androgenic activity is half of that of testosterone. Nonetheless, in real-life settings, it seems that Anadrol is likely to cause more androgenic side effects. It seems that it has to do with the fact that Anadrol is a derivative of dihydrotestosterone (DHT). This is a powerful androgen hormone.

Therefore, it seems like androgenic activity in the body is higher than that on the paper. Yet, it’s important to understand that androgenic activity is very different and individual. Genetics will play a huge role in determining the androgenicity of a steroid.

Androgenic side effects usually include an increase in sebum secretion (oily skin) as well as an increase in acne. It also could increase bodily and facial hair growth, speed up male pattern baldness in men that have this genetic trait as well as increase the aggression in those who are already pretty aggressive by nature. It may also increase male secondary sex characteristics (like voice hoarseness, facial changes, and others).

• Again, it is very closely related to the genetics of each individual. Steroids like Anadrol could indeed increase hair loss, but only if you have this genetic trait which will likely cause hair loss even without steroids. They just speed up the process. But if you are not having the genetics of suffering from acne or hair loss, you may use steroids without such issues.

Estrogenic Side Effects

Anadrol is popular as an extremely estrogenic anabolic and androgenic steroid. That’s why it can cause so much water retention and bloating (you are very likely to experience such issues). However, it’s important to know that estrogenic activity does not originate from the conversion of Oxymetholone into estrogen. Oxymetholone is a derivative of DHT and as with any other derivatives, it will not convert into estrogen through aromatization. It is immune to aromatase enzymes. That’s why, when you use Anadrol, this steroid will not increase your estrogen levels. But it is still heavily estrogenic. How’s that?

Well, Oxymetholone works as an estrogen itself and it binds to estrogen receptors. Therefore, as soon as it binds to the estrogen receptors throughout your body, you are very likely to develop common estrogenic side effects. Again, despite not increasing estrogen levels. The common estrogenic side effects include water retention, bloating, development of gyno, possible fat gain, and may even lead to feeling emotional, losing libido, or erectile dysfunction among others.

Moreover…

The huge problem with Oxymetholone (Anadrol) is that since it does not aromatize into estrogen, aromatase inhibitors (AIs) such as Anastrozole or Exemestane will be ineffective to deal the Anadrol-related estrogenic issues. They will not help deal with any of them like gyno, water retention, or any other.

• The only estrogenic side effect that you can deal with is gynecomastia. That’s with the help of Nolvadex (tamoxifen) which is a SERM. It doesn’t lower estrogen levels, it binds directly to estrogen receptors in the breast tissues blocking estrogen activity. Because of this, you can only control gyno from Anadrol. But you can’t control any other estrogenic side effects.

There’s no defense against water retention and bloating. All you can do is to keep an eye on your diet. Even the changes in your diet are limited in results. If it doesn’t really help, there’s basically nothing you can do.

Oxymetholone Side Effects Conclusion

It’s important to understand that the more powerful a steroid is, the more likely it is to cause side effects. Anadrol (Oxymetholone) is perhaps the most powerful oral steroid and while it means that it will help you bulk up really fast, gaining a lot of muscle and strength, you should be aware of its side effects that can be intense and dangerous.

It is extremely important to use anabolic steroids, especially powerful ones like Anadrol, very carefully. Take appropriate precautions, learn how to use the product correctly, and do not forget about environmental factors. Make sure you do not have any pre-existing health issues before starting the use of steroids, use them correctly and with the proper diet and workout plan.

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